Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Naltrexone is a prescription medication used to reduce the desire to drink by blocking endorphins released when alcohol is consumed. This means individuals no longer receive the same “buzz” from drinking, which over time leads to a reduction in cravings and overall consumption.
When many people first hear about The Sinclair Method (TSM), they assume it's just about taking a pill. Simple, right? Pop naltrexone before drinking, and eventually lose the urge. But here's the truth: success on TSM isn't just about the medication — it's about the method, the mindset, and most importantly, the support.
The Sinclair Method (TSM) offers a revolutionary way to overcome alcohol dependence. Unlike traditional abstinence-based recovery, TSM allows individuals to continue drinking while taking medication that gradually reduces their desire for alcohol. This process, known as pharmacological extinction, helps individuals regain control over their drinking habits without the pressure of complete sobriety from the start.
For decades, the idea that "once an alcoholic, always an alcoholic" has dominated conversations about addiction. This belief suggests that those who struggle with alcohol use disorder (AUD) must either embrace lifelong abstinence or face inevitable relapse. However, with advancements in medical research, treatment approaches, and personal choice, this old concept no longer holds up.