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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Top 5 FAQs About The Sinclair Method

Top 5 FAQs About The Sinclair Method

Published on: 10/03/2025

The Sinclair Method is a treatment approach for Alcohol Use Disorder (AUD) that involves taking the medication naltrexone before consuming alcohol. Unlike traditional abstinence-based treatments, TSM allows individuals to continue drinking while the medication works to reduce cravings over time. This process, known as pharmacological extinction, helps individuals regain control over their drinking habits.

The Sinclair Method (TSM)
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