Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Understanding the science of addiction is crucial for anyone on the path to recovery or supporting a loved one through it. At the core of addiction lies a powerful biochemical mechanism driven by the brain’s natural reward system—most notably, endorphins. These feel-good chemicals play a pivotal role in reinforcing behaviours, and when substances like alcohol exploit this system, the result can be a cycle that’s difficult to break.
When it comes to building healthier habits around alcohol, knowledge truly is power. Understanding what you're drinking—and how much—is the first step in regaining control. That’s where the Free Drink Calculator from Rethink Drink becomes invaluable. Whether you're just becoming sober curious or actively using the Sinclair Method, this simple, user-friendly tool offers a vital layer of insight.
A science-based approach called The Sinclair Method (TSM) is gaining visibility in the UK and Ireland. At its core is Naltrexone, a medication that rewires the brain’s response to alcohol.
When we think of recovery from alcohol dependency, the image that often springs to mind is a circle of people saying, “Hi, I’m John, and I’m an alcoholic.” This familiar ritual of Alcoholics Anonymous (AA) has been a cornerstone of addiction recovery since the 1930s. But as society changes, and science advances, many are asking: is AA becoming outdated?