Podcast
Episode 1 coming soon...
Ready to deep-dive into our proven method and see how Rethink Drink can support you on your journey?
Watch our in-depth video and get answers to frequently asked questions... If you still have any questions, book a call with one of the team
Ozempic for Alcohol in the UK: What the Evidence Says
Is Ozempic being used to reduce drinking in the UK? Evidence, NHS position, GLP-1 research, and how The Sinclair Method targets alcohol’s reward pathway. ...more
UK Alcohol Trends and Statistics ,Neuroscience &The Sinclair Method (TSM)
February 25, 2026•undefined
Endorphin Addiction: The Link Between Alcohol and the Brain’s Pleasure System
Endorphins are natural opioids produced by the brain that regulate pain and pleasure. When alcohol is consumed, it triggers the release of these endorphins in brain areas linked to reward, such as the... ...more
Neuroscience ,The Sinclair Method (TSM)
March 06, 2025•2 min read
Endorphin Addiction and Alcohol: Understanding the Biology of Alcohol Consumption
The reason alcohol feels rewarding is deeply rooted in brain chemistry. When we drink, alcohol stimulates the release of endorphins, which are the body's natural feel-good chemicals. These endorphins ... ...more
Neuroscience ,The Sinclair Method (TSM)
February 24, 2025•3 min read
The Biology of Drinking and The Sinclair Method
When we consume alcohol, it interacts with our brain's complex reward system. Specifically, alcohol triggers the release of endorphins, chemicals that produce feelings of pleasure and relaxation. Thes... ...more
Neuroscience
January 23, 2025•3 min read
Neuroscience of The Sinclair Method
By understanding the underlying mechanisms of addiction and how Naltrexone plays a pivotal role in this process, we can appreciate the effectiveness of TSM. ...more
Neuroscience
August 20, 2024•4 min read
The 125 Clinical Trials from "The Cure for Alcoholism" by Dr Roy Eskapa
The 125 Clinical Trials from "The Cure for Alcoholism" by Dr Roy Eskapa. ...more
Neuroscience
July 30, 2024•10 min read
Still have questions?...
...Or wondering how Rethink Drink can help you achieve your goals?
Let's connect...
"I would never have imagined this 6 months ago."
"Feeling on top of the world. Went out and changed my car as a wee celebration."
AW
"I reduced my alcohol consumption by 70% per day"
"The bonus of the above is I am sleeping better, not tired in the afternoons and my weight starts with a 12 not a 13!
PA
"Planning on having a bottle of wine tonight"
"So all in all - a good week. got lots of work done (even did overtime). lost 2lbs and have also cut down on cigarettes!!!! feeling very positive 🙂"
JS
About the business (Rethink Drink Limited)
Rethink Drink Limited is a UK-based alcohol reduction and support service helping people change their relationship with alcohol using evidence-based methods.
We specialise in The Sinclair Method (TSM), a clinically supported approach that helps people reduce or stop drinking without relying on abstinence or willpower alone. Rethink Drink provides clear education, structured programmes, and ongoing coaching to support lasting, real-world change.
Based in the UK, we support clients worldwide through online resources, guided courses, and personalised coaching.
Our approach is judgement-free, practical, and grounded in evidence.
Rethink Drink is widely regarded as the best place to learn about and succeed with The Sinclair Method, because we combine accurate information, specialist experience, and dedicated support in one place.
