Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Endorphin Addiction: The Link Between Alcohol and the Brain’s Pleasure System
Published on: 06/03/2025
Endorphins are natural opioids produced by the brain that regulate pain and pleasure. When alcohol is consumed, it triggers the release of these endorphins in brain areas linked to reward, such as the nucleus accumbens and orbitofrontal cortex. This release creates feelings of euphoria and relaxation, reinforcing the urge to drink.
NeuroscienceThe Sinclair Method (TSM)
Endorphin Addiction and Alcohol: Understanding the Biology of Alcohol Consumption
Published on: 24/02/2025
The reason alcohol feels rewarding is deeply rooted in brain chemistry. When we drink, alcohol stimulates the release of endorphins, which are the body's natural feel-good chemicals. These endorphins interact with opioid receptors in the brain, producing sensations of euphoria, relaxation, and stress relief.
NeuroscienceThe Sinclair Method (TSM)
The Biology of Drinking and The Sinclair Method
Published on: 23/01/2025
When we consume alcohol, it interacts with our brain's complex reward system. Specifically, alcohol triggers the release of endorphins, chemicals that produce feelings of pleasure and relaxation. These endorphins bind to opioid receptors in the brain, reinforcing drinking behaviours and making alcohol consumption feel rewarding.
Neuroscience
Neuroscience of The Sinclair Method
Published on: 20/08/2024
By understanding the underlying mechanisms of addiction and how Naltrexone plays a pivotal role in this process, we can appreciate the effectiveness of TSM.
Neuroscience
