Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
When we think of recovery from alcohol dependency, the image that often springs to mind is a circle of people saying, “Hi, I’m John, and I’m an alcoholic.” This familiar ritual of Alcoholics Anonymous (AA) has been a cornerstone of addiction recovery since the 1930s. But as society changes, and science advances, many are asking: is AA becoming outdated?
"Why don’t they just stop?" It’s a familiar question — one that often leads to frustration, judgement, and misunderstanding. For years, alcohol dependency has been viewed through the lens of morality or self-control. But science paints a different picture: alcohol use disorder (AUD) is not a lifestyle choice, but a chronic condition shaped by changes in brain function.
In the United Kingdom, the Chief Medical Officers advise that to keep health risks from alcohol low, adults should drink no more than 14 units of alcohol per week. This guideline is the same for both men and women, and it is best to spread the intake across three or more days rather than consuming it all at once
When many people first hear about The Sinclair Method (TSM), they assume it's just about taking a pill. Simple, right? Pop naltrexone before drinking, and eventually lose the urge. But here's the truth: success on TSM isn't just about the medication — it's about the method, the mindset, and most importantly, the support.