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Sinclair Method Studies

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Gradual Reduction with The Sinclair Method: Why It Works

Gradual Reduction with The Sinclair Method: Why It Works

That’s where The Sinclair Method (TSM) shines. This innovative approach offers an alternative: gradual reduction, using the medication naltrexone to change your brain’s response to alcohol, one drink at a time.

The Sunday Reset

Every Sunday, we share a 2-minute insight into the logic of the Sinclair Method.

Join thousands of others for our weekly newsletter and change how you see the problem,

because when you change the way you look at things, the things you look at change.

… There’s a reason we’re called Rethink Drink!

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