Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
The Science Behind The Sinclair Method
Bruce Rose Published on: 24/09/2025
Alcohol has long been used to numb, to celebrate, and to escape—the story quickly turns from one of choice to compulsion. Traditional recovery methods often push for immediate abstinence, yet many find this approach unsustainable.
The Sinclair Method (TSM)
Claudia Christian: Advocate for the Sinclair Method
Bruce Rose Published on: 23/09/2025
Claudia Christian, best known for her acting roles in Babylon 5 and 9‑1‑1, is also the founder and CEO of the C Three Foundation. She is a passionate proponent of The Sinclair Method as a science-based medication-assisted approach to alcohol use disorder
The Sinclair Method (TSM)
Do I Need a Detox to Start The Sinclair Method?
Bruce Rose Published on: 22/09/2025
For many, the word “detox” brings up images of cold-turkey abstinence, withdrawal symptoms, and white-knuckled willpower. But what if we told you that there’s a method that flips this idea on its head?
The Sinclair Method (TSM)
The Role of Endorphins in Alcohol Dependency: What You Need to Know
Bruce Rose Published on: 18/09/2025
Endorphins are naturally occurring chemicals in the brain that help us manage pain and boost pleasure. Often called the body’s “natural opioids”, they are released during activities like exercise, laughing, eating, and social bonding. When endorphins flood the brain, we feel good — relaxed, happy, or even euphoric.
The Sinclair Method (TSM)
Can I Get Naltrexone from My GP? What You Need to Know
Bruce Rose Published on: 17/09/2025
Naltrexone is a powerful tool for reducing alcohol cravings, especially when used as part of the Sinclair Method (TSM). But if you’re considering this approach, a key question often arises: Can I get Naltrexone from my GP?
The Sinclair Method (TSM)
Ozempic vs Naltrexone: Understanding the Key Differences for Alcohol Recovery
Bruce Rose Published on: 16/09/2025
Ozempic and naltrexone are very different medications, each targeting distinct areas of the brain and body. Ozempic is designed to manage type 2 diabetes and promote weight loss by reducing hunger. Naltrexone is specifically designed to reduce cravings and the rewarding effects of alcohol.
The Sinclair Method (TSM)
