Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Is Alcohol Recovery Changing the Model? A New Era with the Sinclair Method
Bruce Rose Published on: 04/06/2025
The landscape of alcohol recovery is undergoing a major transformation. For decades, abstinence was seen as the only viable path to recovery—often rigid, binary, and stigmatised. But science and innovation are rewriting that narrative. Today, we stand at the threshold of a new paradigm—one rooted in neuroscience, evidence, and personal empowerment.
The Sinclair Method (TSM)
Why Is It So Difficult to Stop Drinking? The Science Behind Endorphins and Incomplete Treatment
Bruce Rose Published on: 27/05/2025
Many of us assume that stopping drinking is simply about self-control. But if you've ever tried to cut down—or stop entirely—you'll know it's not that simple. It often feels like you're fighting your own brain. And in many ways, that’s exactly what’s happening.
The Sinclair Method (TSM)
Does The Sinclair Method Work? Evidence, Success Rates & What to Expect
Bruce Rose Published on: 22/05/2025
The Sinclair Method (TSM) is a medically supervised treatment for Alcohol Use Disorder (AUD) that utilises the opioid-blocking medication naltrexone. This treatment works by weakening the association between alcohol and the brain’s reward system. Naltrexone is taken one hour before drinking, blocking endorphins that would normally reinforce the behaviour.
The Sinclair Method (TSM)
What is The Sinclair Method? Discover the Gold Standard for Alcohol Recovery in the UK & Ireland
Published on: 11/04/2025
The Sinclair Method (TSM) is a medically proven approach to reducing and overcoming alcohol dependence – one that flips conventional treatment on its head. Rather than asking you to quit drinking from day one, TSM invites you to do something far simpler: take a tablet of naltrexone one hour before drinking.
The Sinclair Method (TSM)
