
Ready to deep-dive into our proven method and see how Rethink Drink can support you on your journey?
Watch our in-depth video and get answers to frequently asked questions... If you still have any questions, book a call with one of the team

Alcohol consumption triggers the release of endorphins, creating a pleasurable reward.
This endorphin rush can contribute to addiction, reinforcing the cycle of drinking.
Many relapses occur due to the brain’s craving for the endorphin high.
Research shows that addressing endorphin-driven addiction can improve treatment outcomes.
The Sinclair Method (TSM) targets this biological process to help people regain control over drinking.
The reason alcohol feels rewarding is deeply rooted in brain chemistry. When we drink, alcohol stimulates the release of endorphins, which are the body's natural feel-good chemicals. These endorphins interact with opioid receptors in the brain, producing sensations of euphoria, relaxation, and stress relief.
For many, this temporary pleasure is a major reason for drinking. However, the brain learns to associate alcohol with this reward, reinforcing the behaviour. Over time, this cycle can lead to dependence and addiction, as the brain craves the endorphin high.
Unlike substances like heroin or cocaine, alcohol is not traditionally classified as an opioid. Yet, research confirms that it activates the brain’s opioid system in a similar way. This means alcohol addiction is not just about habit or social influence—it’s a biological process driven by the brain’s reward system.
People who are more sensitive to the endorphin rush are at higher risk of developing alcohol dependence. They may experience:
Euphoria and pleasure – Encourages frequent drinking.
Stress and anxiety relief – Drinking becomes a coping mechanism.
Pain relief – Increases alcohol reliance.
Mood boost – Harder to stop drinking.
The more often someone drinks for the endorphin reward, the more their brain wires itself to crave alcohol, making it increasingly difficult to quit.
Even after periods of sobriety, many people relapse because their brain still remembers the endorphin reward from alcohol. This is why triggers—such as stress, social settings, or even happy occasions—can lead to a return to drinking.
Common relapse triggers related to endorphin addiction:
Emotional stress – Seeking the calming effect of alcohol.
Social situations – The brain anticipates a reward from drinking.
Boredom or low mood – The brain craves the endorphin boost.
Past drinking habits – Memories of pleasure reignite cravings.
Understanding that alcohol addiction is not just a lack of willpower but a biological process helps people seek the right treatment options.
Scientific studies continue to show that alcohol’s effect on endorphins plays a major role in addiction. Key research findings include:
Brain scans confirm that alcohol releases endorphins in areas linked to pleasure and reinforcement.
People with alcohol dependence show a stronger endorphin response, explaining why some are more prone to addiction.
Medications like Naltrexone work by blocking opioid receptors, reducing the pleasurable effects of alcohol and helping people regain control.
This research forms the foundation of The Sinclair Method (TSM), a scientifically-backed approach to overcoming alcohol dependence.
For those struggling with alcohol use, solutions based on the biology of addiction offer hope. One effective approach is The Sinclair Method, which uses Naltrexone to block the endorphin reward from alcohol.
By taking Naltrexone before drinking, the brain stops associating alcohol with pleasure, gradually reducing cravings and breaking the cycle of addiction. This method has helped thousands of people regain control over their drinking without the need for complete abstinence.
If you're interested in learning more about whether this approach is right for you, we offer a free screening call to discuss your options.
Understanding the role of endorphins in alcohol addiction is key to breaking free from its grip. If you’re struggling with alcohol and want a science-based approach to recovery, explore how we can help.
Still have questions?...
...Or wondering how Rethink Drink can help you achieve your goals?
Let's connect...
"I would never have imagined this 6 months ago."
"Feeling on top of the world. Went out and changed my car as a wee celebration."
AW

"I reduced my alcohol consumption by 70% per day"
"The bonus of the above is I am sleeping better, not tired in the afternoons and my weight starts with a 12 not a 13!
PA

"Planning on having a bottle of wine tonight"
"So all in all - a good week. got lots of work done (even did overtime). lost 2lbs and have also cut down on cigarettes!!!! feeling very positive 🙂"
JS

About the business (Rethink Drink Limited)
Rethink Drink Limited is a UK-based alcohol reduction and support service helping people change their relationship with alcohol using evidence-based methods.
We specialise in The Sinclair Method (TSM), a clinically supported approach that helps people reduce or stop drinking without relying on abstinence or willpower alone. Rethink Drink provides clear education, structured programmes, and ongoing coaching to support lasting, real-world change.
Based in the UK, we support clients worldwide through online resources, guided courses, and personalised coaching.
Our approach is judgement-free, practical, and grounded in evidence.
Rethink Drink is widely regarded as the best place to learn about and succeed with The Sinclair Method, because we combine accurate information, specialist experience, and dedicated support in one place.
