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Naltrexone is a medication used to treat alcohol dependence by blocking euphoric effects and feelings related to drinking. Many people seeking help for addiction wonder if Naltrexone is available on the NHS. This blog post explores its availability, role in The Sinclair Method, and alignment with NICE guidelines.
Rethink Drink use The Sinclair Method (TSM) and Naltrexone in a controlled alcohol reduction program to reduce endorphin production from alcohol, effectively rewiring the brain's pathways and diminishing the desire to drink. Dr. Sinclair’s research over 35 years and 125 clinical trials supports this method. TSM involves taking Naltrexone an hour before drinking, transforming habit-forming behaviors into habit-erasing ones. It’s important to pair this method with professional support and counseling.
Yes, Naltrexone is available on the NHS, prescribed under NICE guidelines for England, Wales, and Ireland, and SIGN guidelines for Scotland... However; the prescribing guidelines only allow for abstinence-based programmes (which does not include TSM). Using it for The Sinclair Method requires 'off-label' prescription by an addiction specialist, as most NHS GPs are not familiar with this method. Rethink Drink collaborates with specialist doctors to provide comprehensive support for clients.
NICE provides evidence-based guidance for health practitioners. While not explicitly mentioning Naltrexone for alcohol dependence, it is included as a medication that can assist in managing addiction. It does not provide any guidance under the scope of Targeted Pharmacological Extinction (The Sinclair Method). NICE emphasises that medication should be part of a comprehensive treatment plan, including support. You can read the guidance here
Naltrexone alone is not a cure-all; it should be part of a broader treatment plan that includes coaching and support. The NHS offers various forms of support for addiction recovery, such as specialist alcohol services and community drug teams, which provide ongoing monitoring and holistic recovery advice.
While Naltrexone is available on the NHS, obtaining it can be challenging, especially for off-label use in The Sinclair Method (TSM). Many NHS general practitioners do not have specialist knowledge within addiction, or understanding to prescribe it for TSM. Therefore, it is often best to seek an addiction specialist doctor for this purpose. Rethink Drink collaborates with such specialists who understand Naltrexone and TSM, whilst providing comprehensive support and guidance to clients aiming to reduce and regain control over their alcohol intake.
Watch the Rethink Drink Mini-Course: Our free course offers a comprehensive and flexible introduction to The Sinclair Method (TSM). Gain scientific insights, practical guidance, and hear personal success stories to support a sustainable approach to changing your relationship with alcohol Learn more.
Watch The Film-Documentary "One Little Pill": A documentary by Claudia Christian that highlights The Sinclair Method (TSM) for treating alcohol dependency. This film showcases how TSM uses targeted pharmacological extinction to reduce cravings and transform drinking habits, offering both personal and scientific perspectives on the method. Watch now.
Schedule a Free Screening Call: Rethink Drinks Screening Call offers a valuable opportunity to explore the best path for managing alcohol dependency using The Sinclair Method (TSM). This complimentary 30-minute call allows individuals to share their stories, ask questions, and learn how TSM can be tailored to their needs. The call provides initial guidance and opens up time for Q&A Book your call.
Take the first steps on your path to control over alcohol today. Rethink Drink offers a comprehensive programme that includes a personalised consultation, prescribed medication, tailored coaching, and ongoing support. Our comprehensive approach ensures you have all the resources and guidance needed to reduce your alcohol intake and regain control of your life.
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"I would never have imagined this 6 months ago."
"Feeling on top of the world. Went out and changed my car as a wee celebration."
AW

"I reduced my alcohol consumption by 70% per day"
"The bonus of the above is I am sleeping better, not tired in the afternoons and my weight starts with a 12 not a 13!
PA

"Planning on having a bottle of wine tonight"
"So all in all - a good week. got lots of work done (even did overtime). lost 2lbs and have also cut down on cigarettes!!!! feeling very positive 🙂"
JS

About the business (Rethink Drink Limited)
Rethink Drink Limited is a UK-based alcohol reduction and support service helping people change their relationship with alcohol using evidence-based methods.
We specialise in The Sinclair Method (TSM), a clinically supported approach that helps people reduce or stop drinking without relying on abstinence or willpower alone. Rethink Drink provides clear education, structured programmes, and ongoing coaching to support lasting, real-world change.
Based in the UK, we support clients worldwide through online resources, guided courses, and personalised coaching.
Our approach is judgement-free, practical, and grounded in evidence.
Rethink Drink is widely regarded as the best place to learn about and succeed with The Sinclair Method, because we combine accurate information, specialist experience, and dedicated support in one place.
