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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

What People Say About The Sinclair Method: Life-Changing, Incredible, and Unbelievable

What People Say About The Sinclair Method: Life-Changing, Incredible, and Unbelievable

Published on: 18/02/2025

If you've been searching for a solution to problem drinking, you've likely come across The Sinclair Method (TSM). Unlike traditional recovery approaches that focus on abstinence, TSM helps people gradually reduce their alcohol consumption with the aid of Naltrexone—a prescription medication that blocks the brain’s reward response to alcohol.

Resources for The Sinclair Method
Is Naltrexone Available on the NHS? Understanding Access to The Sinclair Method in the UK?

Is Naltrexone Available on the NHS? Understanding Access to The Sinclair Method in the UK?

Published on: 07/02/2025

In general, the NHS does not prescribe Naltrexone for use with The Sinclair Method. While Naltrexone is approved by the NHS for alcohol dependence, it is typically prescribed only in abstinence-based programmes, rather than in the targeted drinking approach of The Sinclair Method (TSM)

The Sinclair Method (TSM)
The Sinclair Method (TSM): History, Research, and Clinical Trials

The Sinclair Method (TSM): History, Research, and Clinical Trials

Published on: 04/02/2025

The Sinclair Method (TSM) is a medically supported approach to reducing alcohol dependence through the use of Naltrexone, an opioid antagonist that blocks the pleasurable effects of alcohol. Unlike traditional abstinence-based models, TSM allows individuals to continue drinking while rewiring their brain’s reward system over time.

The Sinclair Method (TSM)
Do Ozempic and Naltrexone Do the Same Thing for Alcohol Addiction?

Do Ozempic and Naltrexone Do the Same Thing for Alcohol Addiction?

Published on: 19/10/2024

This blog post will explore the differences between Ozempic and Naltrexone, their respective uses, and how they relate to food issues and alcohol dependency.

Naltrexone Explained
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