Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
If you've been searching for a solution to problem drinking, you've likely come across The Sinclair Method (TSM). Unlike traditional recovery approaches that focus on abstinence, TSM helps people gradually reduce their alcohol consumption with the aid of Naltrexone—a prescription medication that blocks the brain’s reward response to alcohol.
In general, the NHS does not prescribe Naltrexone for use with The Sinclair Method. While Naltrexone is approved by the NHS for alcohol dependence, it is typically prescribed only in abstinence-based programmes, rather than in the targeted drinking approach of The Sinclair Method (TSM)
The Sinclair Method (TSM) is a medically supported approach to reducing alcohol dependence through the use of Naltrexone, an opioid antagonist that blocks the pleasurable effects of alcohol. Unlike traditional abstinence-based models, TSM allows individuals to continue drinking while rewiring their brain’s reward system over time.
This blog post will explore the differences between Ozempic and Naltrexone, their respective uses, and how they relate to food issues and alcohol dependency.