Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
The Sinclair Method: The Benefits of Controlling Drinking with Naltrexone
Many people struggle with over drinking but feel resistant to total abstinence. The Sinclair Method (TSM) offers a science-based solution that helps individuals moderate their drinking naturally. Rather than relying on willpower alone, TSM uses Naltrexone, an opioid antagonist, to gradually reduce the brain’s reinforcement of alcohol consumption.
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