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20 Key Facts about The Sinclair Method

20 Key Facts about The Sinclair Method

April 20, 20243 min read

20 Key Facts about The Sinclair Method

Key Takeaways

  • Understanding TSM: Learn how The Sinclair Method (TSM) offers a unique approach to managing alcohol use disorder (AUD) using Naltrexone.

  • Effectiveness and Accessibility: Discover the success rate and global acceptance of TSM.

  • Support and Resources: Uncover available support systems and resources, including a mini-course and social media platforms.


Dive into 20 essential facts about The Sinclair Method

The Sinclair Method (TSM) represents a significant shift in treating alcohol use disorder (AUD) through a process known as pharmacological extinction. Here are 20 essential facts about TSM that provide insight into its functionality, effectiveness, and how it can be a game-changer for many individuals struggling with AUD.

  1. What is The Sinclair Method? TSM is a treatment for AUD that uses the opioid antagonist Naltrexone to change the brain's response to alcohol, effectively reducing the desire to drink over time.

  2. Based on Pharmacological Extinction: The method uses the principle of pharmacological extinction, where Naltrexone blocks the endorphins released by drinking alcohol, gradually reducing the pleasure and thus the craving.

  3. Evidence-Based Success: Studies show that TSM has a 78% success rate in reducing drinking levels to a controlled state or achieving complete abstinence.

  4. Non-Abstinence Focused: Unlike traditional abstinence methods, TSM does not require you to stop drinking immediately. It allows for a gradual reduction in alcohol use.

  5. Naltrexone as a Key Component: Naltrexone is taken one hour before drinking, which helps diminish the reinforcing effects of alcohol over time.

  6. Flexible Treatment Approach: TSM offers a flexible approach that can be tailored to individual needs, making it a practical option for many.

  7. Global Acceptance: While originating in Finland, TSM is now recognised and used worldwide as an effective treatment for AUD.

  8. Affordable and Accessible: Naltrexone, the medication used in TSM, is relatively affordable and widely available in many countries.

  9. Minimal Side Effects: Naltrexone is generally well-tolerated, with few side effects, making it a viable option for long-term use.

  10. Support Through Technology: Various apps and online platforms support individuals following TSM, offering tracking tools and community support.

  11. Duration of Treatment: The duration of TSM varies, but many individuals see significant changes in their drinking habits within three to four months.

  12. Scientific Backing: TSM is backed by numerous scientific studies that confirm its efficacy in reducing alcohol dependence.

  13. Increased Effectiveness Over Time: The effectiveness of TSM increases over time as the association between alcohol and pleasure weakens.

  14. Personal Empowerment: TSM empowers individuals by allowing them to control their drinking rather than being controlled by it.

  15. Comprehensive Approach: It can be combined with other treatment modalities like cognitive behavioural therapy to enhance outcomes.

  16. Not a Standalone Cure: While highly effective, TSM is best used as part of a broader recovery strategy that includes support and lifestyle changes.

  17. Online Community Support: A robust online community exists for those using TSM, including forums, social media groups, and Rethink Drink's Facebook page.

  18. Educational Resources: For those new to TSM, Rethink Drink offers a mini-course that provides essential information and guidance.

  19. Accessibility Through Telemedicine: Naltrexone and TSM guidance are accessible through telemedicine services, making it easier for those in remote areas to receive treatment.

  20. Continued Research and Development: Ongoing research aims to enhance the understanding and efficacy of TSM, promising future improvements and broader implementation.


These facts highlight the innovative approach of The Sinclair Method in treating alcohol use disorder. By utilizing Naltrexone to reduce alcohol cravings gradually, TSM offers a hopeful perspective for many who struggle with traditional abstinence-based methods. For further insights and support, consider exploring additional resources, such as Rethink Drink's YouTube channel, which offers a wealth of information and community engagement.

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