Naltrexone, The Sinclair Method UK
Key Takeaways
The Sinclair Method (TSM) uses naltrexone to gradually reduce alcohol cravings through pharmacological extinction.
Rethink Drink offers a UK-based online programme with medical supervision and structured support.
Naltrexone blocks the brain’s reward response to alcohol without requiring immediate abstinence.
This evidence-based method supports real-world drinking reduction without stigma or group therapy.
Access to naltrexone through the NHS remains limited, making private support crucial.
What Is the Sinclair Method?
The Sinclair Method is a science-based approach to treating alcohol use disorder (AUD), offering a middle ground between abstinence and heavy drinking. Unlike traditional recovery paths, it doesn’t require quitting immediately or joining support groups. Instead, it uses the medication naltrexone, taken one hour before drinking, to weaken alcohol’s pleasurable effects.
By consistently using naltrexone before alcohol consumption, the brain gradually unlearns its reward association with drinking—a process called pharmacological extinction. Over time, cravings diminish and many people naturally reduce or stop drinking altogether.
This approach is ideal for those who want to take back control over their drinking without the pressure of “all or nothing” recovery models.
How Rethink Drink Supports The Sinclair Method UK
While naltrexone is approved for alcohol dependence on the NHS, it’s rarely prescribed due to systemic limitations. That’s where Rethink Drink steps in, offering private, online access to the Sinclair Method through a medically supervised programme.
Here’s what’s included in our support:
A free screening call to determine suitability for the method
One-to-one medical consultation with a qualified professional
Prescription for naltrexone tablets, typically enough for 6 months
Ongoing support through regular check-ins
Tools to track alcohol consumption and behavioural patterns
Personalised support that adapts to your pace and lifestyle
This structure allows for real change without rehab, group therapy, or shame. You can begin today by booking your free screening call.
Why Naltrexone Works: The Science Behind It
Naltrexone works by blocking opioid receptors in the brain, which prevents the release of endorphins that usually follow alcohol consumption. This disrupts the reinforcement loop that drives compulsive drinking.
Key benefits of naltrexone include:
It is non-addictive and safe for long-term use
It does not require abstinence—you take it before you drink
Side effects are usually mild and temporary (e.g. nausea or fatigue)
The medication is approved for alcohol dependence in the UK
When used correctly, it leads to natural reduction in cravings
With consistent use, individuals report a significant drop in drinking within weeks to months, without the stress of total abstinence.
Real Results for Real People
Clients using the Sinclair Method through Rethink Drink often experience the following:
Reduced frequency and intensity of drinking sessions
Improved mental clarity, sleep, and physical health
Freedom from shame and guilt tied to failed attempts at quitting
Greater confidence in their ability to change
Stronger boundaries around drinking choices
Many users find this method more sustainable than traditional abstinence-based approaches. By working with biology, not against it, they see real, lasting results.
Explore our full range of support by visiting the Rethink Drink homepage.
Why Choose The Sinclair Method UK Over Traditional Recovery?
The Sinclair Method offers a flexible, empowering route to recovery that contrasts sharply with conventional rehab or 12-step programmes. Here’s how it compares:
No requirement to stop drinking immediately
Entirely online – no need to attend in-person meetings
Scientifically proven with a success rate of up to 78%
Affordable and discreet, without long waiting lists
Focused on you – no group sharing, just personal guidance
For anyone who feels stuck between “drinking too much” and “not ready to quit,” this method offers an actionable, compassionate middle path.
Take your first step with our free mini course to learn more about how the Sinclair Method works in real life.
You’re in Control, One Drink at a Time
With the right tools, change doesn’t have to be dramatic or punishing. The Sinclair Method allows you to reduce drinking gradually, regain autonomy, and build a healthier relationship with alcohol—on your terms.
Rethink Drink is here to guide you through every step of that journey, offering science-backed strategies, expert medical care, and a judgment-free environment.
Book your free screening call today and take the first step toward freedom.
