Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
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The Sinclair Method didn’t originate in a corporate lab or a detox facility—it started in a Helsinki research centre. Dr John David Sinclair, a behavioural psychologist from the United States, moved to Finland in the early 1970s after completing his PhD. There, he joined Alko Laboratories, the research arm of Finland’s state alcohol monopoly, which would later become part of the country’s National Public Health Institute.
When it comes to changing our relationship with alcohol, many of us are told there's only one way: stop drinking completely, right now. But what if that approach is too harsh—too unforgiving—for where we're at emotionally, psychologically, or even physically?
A science-based approach called The Sinclair Method (TSM) is gaining visibility in the UK and Ireland. At its core is Naltrexone, a medication that rewires the brain’s response to alcohol.