Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

My first drink on naltrexone using The Sinclair Method. Here’s what really happened and why it changed everything.

Is Ozempic being used to reduce drinking in the UK? Evidence, NHS position, GLP-1 research, and how The Sinclair Method targets alcohol’s reward pathway.

Join The Sunday Reset, a free 2-minute weekly email from Rethink Drink offering calm, practical insights into alcohol and The Sinclair Method.

Nul Health has raised €840,000 in UK seed funding. What does ChooseNul.com mean for The Sinclair Method and alcohol treatment delivery in Britain?

Drinking more after Dry January? Discover how the alcohol deprivation effect increases cravings and why abstinence alone doesn’t work for everyone.

Considering The Sinclair Method? Book a confidential UK consultation. No pressure, just clarity about your next steps.
The Sunday Reset
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Join thousands of others for our weekly newsletter and change how you see the problem,
because when you change the way you look at things, the things you look at change.
… There’s a reason we’re called Rethink Drink!
