Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
The Role of Endorphins in Alcohol Dependency: What You Need to Know
Endorphins are naturally occurring chemicals in the brain that help us manage pain and boost pleasure. Often called the body’s “natural opioids”, they are released during activities like exercise, laughing, eating, and social bonding. When endorphins flood the brain, we feel good — relaxed, happy, or even euphoric.
Why Alcohol Dependency Is So Difficult to Break – The Endorphin Connection and the Sinclair Method
Alcohol dependency isn’t about weakness or moral failure. It’s a complex condition involving the brain’s natural reward mechanisms. When we drink alcohol, our brains release endorphins—feel-good chemicals that act on the same receptors as opioids. This creates a pleasurable feedback loop, making it more likely that we’ll continue drinking to chase that feeling.
The Sunday Reset
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