Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

The Biology of Drinking and The Sinclair Method

Published on: 23/01/2025

When we consume alcohol, it interacts with our brain's complex reward system. Specifically, alcohol triggers the release of endorphins, chemicals that produce feelings of pleasure and relaxation. These endorphins bind to opioid receptors in the brain, reinforcing drinking behaviours and making alcohol consumption feel rewarding.

Neuroscience

Neuroscience of The Sinclair Method

Published on: 20/08/2024

By understanding the underlying mechanisms of addiction and how Naltrexone plays a pivotal role in this process, we can appreciate the effectiveness of TSM.

Neuroscience