Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

This shift is particularly evident in articles published by reputable sources such as The Telegraph and The Times, which have highlighted innovative approaches to managing alcohol use. One such approach is the Sinclair Method, a treatment that utilises Naltrexone to help individuals reduce their drinking habits.

The results indicated that around 78% of participants reported a significant decrease in their drinking habits after following this method for several months.
The Sunday Reset
Every Sunday, we share a 2-minute insight into the logic of the Sinclair Method.
Join thousands of others for our weekly newsletter and change how you see the problem,
because when you change the way you look at things, the things you look at change.
… There’s a reason we’re called Rethink Drink!
