Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Why Alcohol Dependency Is So Difficult to Break – The Endorphin Connection and the Sinclair Method
Published on: 06/05/2025
Alcohol dependency isn’t about weakness or moral failure. It’s a complex condition involving the brain’s natural reward mechanisms. When we drink alcohol, our brains release endorphins—feel-good chemicals that act on the same receptors as opioids. This creates a pleasurable feedback loop, making it more likely that we’ll continue drinking to chase that feeling.
The Sinclair Method (TSM)
