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Sinclair Method Studies

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Naltrexone?

Naltrexone?

Naltrexone is a prescription medication known for its ability to block the brain’s opioid receptors, which are responsible for the “reward” feeling associated with alcohol consumption

Who Was Dr David Sinclair, and What Is The Sinclair Method (TSM)?

Who Was Dr David Sinclair, and What Is The Sinclair Method (TSM)?

Dr David Sinclair was a pioneering scientist whose research led to the development of The Sinclair Method (TSM) for Alcohol Use Disorder (AUD) recovery.

The Importance of a Support Programme

The Importance of a Support Programme

Discover why Rethink Drink's support programme is crucial for success with The Sinclair Method

Natural Endorphin Producing Activities

Natural Endorphin Producing Activities

Discover joyful activities that naturally boost your endorphins! From laughter to exercise, find out how to elevate your mood and reduce stress

The Sinclair Method - 78%

The Sinclair Method - 78%

Explaining why The Sinclair Method is so successful with a 78% success rate.

The Sunday Reset

Every Sunday, we share a 2-minute insight into the logic of the Sinclair Method.

Join thousands of others for our weekly newsletter and change how you see the problem,

because when you change the way you look at things, the things you look at change.

… There’s a reason we’re called Rethink Drink!

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