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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Why Alcohol Dependency Is So Difficult to Break – The Endorphin Connection and the Sinclair Method

Why Alcohol Dependency Is So Difficult to Break – The Endorphin Connection and the Sinclair Method

Published on: 06/05/2025

Alcohol dependency isn’t about weakness or moral failure. It’s a complex condition involving the brain’s natural reward mechanisms. When we drink alcohol, our brains release endorphins—feel-good chemicals that act on the same receptors as opioids. This creates a pleasurable feedback loop, making it more likely that we’ll continue drinking to chase that feeling.

The Sinclair Method (TSM)
Is Naltrexone a 'Magic Pill' Like Ozempic, as Written About in the Daily Newspapers?

Is Naltrexone a 'Magic Pill' Like Ozempic, as Written About in the Daily Newspapers?

Published on: 16/10/2024

In recent months, naltrexone has been thrust into the limelight, often compared to the much-discussed diabetes medication Ozempic

The Sinclair Method (TSM)
Why Support is So Important with the Sinclair Method

Why Support is So Important with the Sinclair Method

Published on: 24/09/2024

In this blog post, we will explore why support is crucial when implementing the Sinclair Method and how it can significantly enhance outcomes

The Sinclair Method (TSM)
Introduction to Rethink Drink:

Introduction to Rethink Drink:

Published on: 10/04/2024

An overview of the Rethink Drink Support Programme, its objectives, and who it's for

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