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Sinclair Method Studies

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Why Alcohol Dependency Is So Difficult to Break – The Endorphin Connection and the Sinclair Method

Why Alcohol Dependency Is So Difficult to Break – The Endorphin Connection and the Sinclair Method

Alcohol dependency isn’t about weakness or moral failure. It’s a complex condition involving the brain’s natural reward mechanisms. When we drink alcohol, our brains release endorphins—feel-good chemicals that act on the same receptors as opioids. This creates a pleasurable feedback loop, making it more likely that we’ll continue drinking to chase that feeling.

Is Naltrexone a 'Magic Pill' Like Ozempic, as Written About in the Daily Newspapers?

Is Naltrexone a 'Magic Pill' Like Ozempic, as Written About in the Daily Newspapers?

In recent months, naltrexone has been thrust into the limelight, often compared to the much-discussed diabetes medication Ozempic

Why Support is So Important with the Sinclair Method

Why Support is So Important with the Sinclair Method

In this blog post, we will explore why support is crucial when implementing the Sinclair Method and how it can significantly enhance outcomes

Introduction to Rethink Drink:

Introduction to Rethink Drink:

An overview of the Rethink Drink Support Programme, its objectives, and who it's for

The Sunday Reset

Every Sunday, we share a 2-minute insight into the logic of the Sinclair Method.

Join thousands of others for our weekly newsletter and change how you see the problem,

because when you change the way you look at things, the things you look at change.

… There’s a reason we’re called Rethink Drink!

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