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Sinclair Method Studies

Published on: 11/06/2025

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

What is the History of The Sinclair Method?

What is the History of The Sinclair Method?

What is the History of The Sinclair Method?Bruce Rose
Published on: 09/09/2025

The Sinclair Method, often referred to as TSM, has quietly revolutionised how we understand and treat Alcohol Use Disorder (AUD). Unlike traditional abstinence-only approaches, it offers a scientifically grounded, compassion-driven alternative. But where did it all begin?

The Sinclair Method (TSM)
Does The Sinclair Method Work? A Closer Look Compared to Abstinence-Based Recovery

Does The Sinclair Method Work? A Closer Look Compared to Abstinence-Based Recovery

Published on: 25/03/2025

The Sinclair Method is a form of medication-assisted treatment that uses opioid-blocking medication—typically naltrexone or nalmefene—to retrain the brain’s response to alcohol. The method is based on a process called pharmacological extinction, which reduces the reward associated with alcohol over time.

The Sinclair Method (TSM)
Does The Sinclair Method Work?

Does The Sinclair Method Work?

Published on: 29/06/2024

Does The Sinclair Method work?

The Sinclair Method (TSM)
Comparison of Effectiveness: The Sinclair Method vs Abstinence - Why The Sinclair Method is a Better Model Physically, Emotionally, and Psychologically

Comparison of Effectiveness: The Sinclair Method vs Abstinence - Why The Sinclair Method is a Better Model Physically, Emotionally, and Psychologically

Published on: 19/03/2024

Let's delve into a comparison of their effectiveness, focusing on the physical, emotional, and psychological dimensions of recovery.

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