Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Understanding the Sinclair Method: A Neurological Approach to Alcohol Recovery
Published on: 02/05/2025
The Sinclair Method is a revolutionary approach to treating Alcohol Use Disorder. Instead of requiring people to stop drinking immediately, it uses a medication — Naltrexone — to help gradually reduce alcohol cravings and dependency. Individuals take Naltrexone one hour before drinking, which blocks the opioid receptors in the brain and, over time, extinguishes the reward response to alcohol.
The Sinclair Method (TSM)
