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Sinclair Method Studies

This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.

Gradual Reduction with The Sinclair Method: Why It Works

Gradual Reduction with The Sinclair Method: Why It Works

That’s where The Sinclair Method (TSM) shines. This innovative approach offers an alternative: gradual reduction, using the medication naltrexone to change your brain’s response to alcohol, one drink at a time.

The Importance of a Support Programme Alongside The Sinclair Method

The Importance of a Support Programme Alongside The Sinclair Method

The Sinclair Method (TSM) has emerged as a ground-breaking approach to reducing alcohol consumption through a medication-first strategy. By using Naltrexone to disrupt the brain’s reward cycle, it gradually helps people lose interest in alcohol.

Does Alcohol Reduction Result in Better Sleep?

Does Alcohol Reduction Result in Better Sleep?

Sleep and alcohol have long had a complicated relationship. For many, a nightcap might feel like a shortcut to falling asleep—but is that truly restful sleep? At Rethink Drink, we often see a turning point for clients who reduce their alcohol intake and, sometimes to their surprise, begin to sleep better than they have in years. Let’s unpack the science behind why alcohol reduction often leads to improved sleep quality and how you can make sustainable changes for long-term wellness.

Who Are Rethink Drink? Changing the Face of Alcohol Recovery in the UK

Who Are Rethink Drink? Changing the Face of Alcohol Recovery in the UK

Founded by Matt Brindley and Bruce Rose, Rethink Drink champions an evidence-based, client-centred approach known as The Sinclair Method (TSM). They’re not just another recovery service—they’re redefining what it means to take back control.

Alcohol Statistics in the UK: 25 Years of Change, Challenge and Hope

Alcohol Statistics in the UK: 25 Years of Change, Challenge and Hope

Over the past 25 years, alcohol consumption in the UK has undergone significant transformation. While public health campaigns have increased awareness, the statistics paint a complex picture of progress, stagnation, and new challenges.

Am I Drinking Too Much? A Closer Look at 14 Units and Beyond

Am I Drinking Too Much? A Closer Look at 14 Units and Beyond

It’s a common concern: Am I drinking too much? And with good reason. While 14 units per week is the current UK guideline for low-risk drinking, what really matters is how alcohol fits into your lifestyle and mental health.

The Sunday Reset

Every Sunday, we share a 2-minute insight into the logic of the Sinclair Method.

Join thousands of others for our weekly newsletter and change how you see the problem,

because when you change the way you look at things, the things you look at change.

… There’s a reason we’re called Rethink Drink!

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