Getting a Handle on Your Drinking: How The Sinclair Method is Changing Live
Key Takeaways:
The Sinclair Method (TSM) is a medically-supported, evidence-based approach to reducing alcohol intake over time.
Backed by more than 35 years of research and over 125 clinical trials.
TSM uses naltrexone to reduce the brain’s reward response to alcohol, helping people drink less naturally.
Rethink Drink is the UK’s trusted source for TSM coaching, offering stigma-free support and guidance.
A free screening call is available to help you determine if TSM is right for your goals.
Reassessing Your Relationship with Alcohol
We all enjoy the occasional drink – but when alcohol becomes more than just a way to relax or socialise, it might be time to pause and reflect. Are you drinking more than you used to? Struggling to cut back even when you try? Feeling frustrated or ashamed about it?
You’re not alone – and importantly, there is a proven method that doesn’t require you to go cold turkey or enter rehab. The Sinclair Method helps you get a handle on your drinking gradually, using science – not willpower.
What Is The Sinclair Method?
The Sinclair Method (TSM) is a medical approach to reducing alcohol consumption by taking a targeted medication called naltrexone. This medication works by blocking the endorphin release that occurs when you drink alcohol – which means the "reward" your brain expects starts to disappear.
Over time, drinking becomes less appealing. And with consistent use of naltrexone before drinking, your habits begin to change naturally – this is called pharmacological extinction.
Why TSM Works
Developed by Dr David Sinclair based on decades of neuroscience research
Focuses on retraining your brain to disconnect alcohol from pleasure
Allows for continued drinking during treatment, reducing guilt and resistance
Results in long-term reduction or complete elimination of alcohol cravings
Encourages autonomy and personal responsibility without stigma
Backed by 35+ Years of Research
The Sinclair Method isn’t a trend – it’s backed by rigorous clinical evidence.
Over 35 years of scientific research
More than 125 clinical trials conducted globally
An estimated 78% success rate for long-term drink reduction when followed correctly
Approved use of naltrexone in managing Alcohol Use Disorder (AUD)
Recognised by healthcare professionals worldwide for its unique, harm-reduction approach
Rethink Drink: Leading the Way in the UK
Until recently, access to The Sinclair Method in the UK was limited. That’s why Rethink Drink was founded – to give people across the UK an alternative to traditional treatment options.
We provide everything you need to make TSM work for you:
Friendly, non-judgemental coaching tailored to your pace
Support accessing naltrexone through trusted medical partners
Clear guidance on how to use TSM effectively and safely
Ongoing help with behaviour change, habit tracking, and goal setting
A stigma-free space to take back control of your drinking
Understanding Naltrexone
When used correctly, naltrexone acts like a “mute button” on alcohol’s reward. Rather than getting the buzz or rush you’re used to, drinking starts to feel flat. Over time, your brain loses interest.
Want to dig deeper into how it works? Read our full naltrexone guide to overcoming alcohol cravings for everything you need to know.
Not Sure if It’s Right for You?
We get it – choosing to change your drinking habits is a big step. That’s why we offer a free screening call to help you explore your options without pressure. Whether you’re looking to cut down or quit completely, we’re here to help you make the best decision for your future.
How TSM Compares to Traditional Recovery Methods
TSM does not require you to quit drinking immediately – you reduce over time, at your own pace.
You’re not relying on willpower alone – the medication actively rewires your brain’s response to alcohol.
There’s no “failure” for drinking – every time you take naltrexone and drink, you’re progressing.
You stay in control – you set your goals, and we support your journey without judgement.
No meetings, no shame, no stigma – just science-based support that works with your life.
Want to learn more about how to get a handle on your drinking without judgement, pressure, or shame? Visit Rethink Drink today – and take your first step toward lasting change.