Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
How Long Does It Take for The Sinclair Method to Work?
The Sinclair Method (TSM) is gaining traction as a science-backed way to change our relationship with alcohol. But a common and completely valid question we get is: how long does it take for The Sinclair Method to work?
Gradual Reduction with The Sinclair Method: Why It Works
That’s where The Sinclair Method (TSM) shines. This innovative approach offers an alternative: gradual reduction, using the medication naltrexone to change your brain’s response to alcohol, one drink at a time.
Who Are Rethink Drink? Changing the Face of Alcohol Recovery in the UK
Founded by Matt Brindley and Bruce Rose, Rethink Drink champions an evidence-based, client-centred approach known as The Sinclair Method (TSM). They’re not just another recovery service—they’re redefining what it means to take back control.
Am I Drinking Too Much? A Closer Look at 14 Units and Beyond
It’s a common concern: Am I drinking too much? And with good reason. While 14 units per week is the current UK guideline for low-risk drinking, what really matters is how alcohol fits into your lifestyle and mental health.
Be You Again: How the Sinclair Method Helps Reclaim Your Life
When alcohol begins to reshape who you are, it’s normal to wonder, “Where did I go?” That’s why at Rethink Drink, we’re passionate about helping you be you again—without guilt, shame, or impossible expectations. The Sinclair Method (TSM) offers a science-led path to overcoming alcohol use disorder (AUD) that’s built on trust, not cold turkey. Let’s dive into how it works and why it’s helping thousands reclaim their lives—quietly, powerfully, and with dignity.
Understanding the Sinclair Method: A Neurological Approach to Alcohol Recovery
The Sinclair Method is a revolutionary approach to treating Alcohol Use Disorder. Instead of requiring people to stop drinking immediately, it uses a medication — Naltrexone — to help gradually reduce alcohol cravings and dependency. Individuals take Naltrexone one hour before drinking, which blocks the opioid receptors in the brain and, over time, extinguishes the reward response to alcohol.
The Sunday Reset
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